The First Congregational Church in Chelsea, MA began as the Winnisimmet Congregational Church in 1841 with a sabbath school, ladies benevolent society, and ordination of its first pastor, Isaac P. Langworthy being organized in the same year. The church grew rapidly in its first decade to the point that it decided to colonize itself with Rev. Langworthy, a group of members, the church records, and the name moving to a new building in 1851 while the remaining members became the Broadway Congregational Church. The Broadway Church later changed its name to the Central Congregational Church in Chelsea, MA in 1871. The members that moved and remained as part of the Winnisimmet Church built the Chestnut St edifice in 1852 with the dedication in May 1852. In 1857, some members split from the church to form the Plymouth Congregational Church which only lasted until 1859. In 1858, the second pastor, Rev. Albert H. Plumb took over the pulpit from Rev. Langworthy. In 1874, the name of the church changed to First Congregational Church in Chelsea, but it was often still known colloquially as the Chestnut St church. In 1877, another group of members left to form the Third Congregational Church in Chelsea. However, changing populations and resources needed to support their respective congregations caused the First and Third Churches to work closely together after 1900 until they decided to officially unite in 1905 as one church under the name First Congregational Church in Chelsea with services continuing in Third Church’s Reynolds Ave building. The last services in First Church’s Chestnut St building were held in June 1905 before the building was sold. In 1906, the first pastor of the united church, Rev. Charles N. Thorp, was called and a new church was built on County Rd with a dedication in 1907 to accommodate the growing membership.

In 1946, the Central Congregational Church in Chelsea closed with many of its members and a large portion of its funds going to the First Congregational Church. In 1961, the church voted to join the United Church of Christ. As the 20th century continued, the church grew and changed according to the changes in the Chelsea community before seeing a decline in membership and funds in the beginning of the 21st century. In 2024, the church sold the County Rd building to the city of Chelsea for use by the school district. The current status of the church is ambiguous given the lack of building for regular services and activities, but the members remain active in the Chelsea community.